| Name | SSR 146977 hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5253 |
| Prices | $239.00, $985.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 264618-38-4 |
| Chemical Name | N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-piperidinyl]-N,N-dimethylureahydrochloride |
| Formula | C35H42Cl2N4O2.HCl |
| Molecular Weight | 658.11 |
| Purity | >98 % |
| Description | Potent and selective NK 3 receptor antagonist (K i values are 0.26 and 19.3 nM in CHO cells expressing the human NK 3 and NK 2 receptor respectively). Also inhibits senktide -induced inositol monophosphate formation and intracellular calcium mobilization (IC 50 = 10 nM). |
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