ST 91

• Supplier: Tocris Bioscience
• Catalog: 4337
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 4749-61-5
• Chemical Name: N-(2,6-Diethylphenyl)-4,5-dihydro-1H-imidazol-2-aminehydrochloride
• Formula: C13H19N3.HCl
• Molecular Weight: 253.77
• Purity: >99 %
• Description: α 2 -adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α 2 receptors over α 1 receptors and acts predominantly at non- α 2A -adrenoceptors which may be of the α 2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.

Product References

Characterization of the pharmacology of intrathecally administered alpha-2 - Characterization of the pharmacology of intrathecally administered alpha-2

Takano Y, Yaksh TL. J Pharmacol Exp Ther. 1992 May;261(2):764-72.

Cardiopulmonary effects of the alpha2-adrenoceptor agonists medetomidine and - Cardiopulmonary effects of the alpha2-adrenoceptor agonists medetomidine and

Celly CS, McDonell WN, Black WD. J Pharmacol Exp Ther. 1999 May;289(2):712-20.

Synergistic interactions between two alpha(2)-adrenoceptor agonists, - Synergistic interactions between two alpha(2)-adrenoceptor agonists,

Graham BA, Hammond DL, Proudfit HK. Pain. 2000 Mar;85(1-2):135-43.