Name | Stattic |
---|---|
Supplier | Tocris Bioscience |
Catalog | 2638 |
Prices | $75.00, $309.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 19983-44-9 |
Chemical Name | 6-Nitrobenzo[b]thiophene1,1-dioxide |
Formula | C8H5NO4S |
Molecular Weight | 211.19 |
Purity | >99 % |
Description | Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. |
Supplier Page | Shop |