Stattic

Name Stattic
Supplier Tocris Bioscience
Catalog 2638
Prices $75.00, $309.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 19983-44-9
Chemical Name 6-Nitrobenzo[b]thiophene1,1-dioxide
Formula C8H5NO4S
Molecular Weight 211.19
Purity >99 %
Description Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines.
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