Name | Stressin I |
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Supplier | Tocris Bioscience |
Catalog | 1621 |
Prices | $369.00 |
Sizes | 500 µg |
Function Type | Agonist |
Formula | C203H337N57O56 |
Molecular Weight | 4472.24 |
Description | Potent and selective corticotropin releasing factor receptor-1 (CRF 1 ) agonist (K i values are 1.5 and 224 nM for CRF 1 and CRF 2 receptors respectively). Increases ACTH levels and increases faecal pellet output in vivo following i.p. administration. |
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Rivier J, Gulyas J, Kunitake K, DiGruccio M, Cantle JP, Perrin MH, Donaldson C, Vaughan J, Million M, Gourcerol G, Adelson DW, Rivier C, Tache Y, Vale W. J Med Chem. 2007 Apr 5;50(7):1668-74. Epub 2007 Mar 3.
Bruchas MR, Land BB, Lemos JC, Chavkin C. PLoS One. 2009 Dec 31;4(12):e8528.