| Name | SU 16f |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4101 |
| Prices | $199.00, $825.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 251356-45-3 |
| Chemical Name | 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoicacid |
| Formula | C24H22N2O3 |
| Molecular Weight | 386.44 |
| Purity | >98 % |
| Description | Potent and selective platelet-derived growth factor receptor β (PDGFR β ) inhibitor (IC 50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC 50 = 0.11 μ M). |
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