TACA

Name TACA
Supplier Tocris Bioscience
Catalog 2308
Prices $115.00, $485.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 38090-53-8
Chemical Name trans-4-Aminocrotonicacid
Formula C4H7NO2
Molecular Weight 101.1
Description The trans-isomer of CACA. Potent GABA A agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABA A - ρ agonist.
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Product References

Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation. - Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation.

Johnston GA, Curtis DR, Beart PM, Game CJ, McCulloch RM, Twitchin B. J Neurochem. 1975 Jan;24(1):157-60.

GABAc receptors: relatively simple transmitter -gated ion channels? - GABAc receptors: relatively simple transmitter -gated ion channels?

Johnston GA. Trends Pharmacol Sci. 1996 Sep;17(9):319-23.

Analogues of gamma-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) - Analogues of gamma-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA)

Chebib M, Vandenberg RJ, Johnston GA. Br J Pharmacol. 1997 Dec;122(8):1551-60.