| Name | Talniflumate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5032 |
| Prices | $95.00, $399.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Blocker |
| Cas Number | 66898-62-2 |
| Chemical Name | 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl3-pyridinecarboxylicacidester |
| Formula | C21H13F3N2O4 |
| Molecular Weight | 414.34 |
| Purity | >99 % |
| Description | Calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Possesses anti-inflammatory actions via inhibition of cyclooxygenases and inhibits Cl - /HCO 3 - exchanger activity. Increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome. |
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