Talopram hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2510
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 7013-41-4
• Chemical Name: 1,3-Dihydro-N,3,3-trimethyl-1-phenyl-1-isobenzofuranpropanaminehydrochloride
• Formula: C20H25NO.HCl
• Molecular Weight: 331.88
• Purity: >99 %
• Description: Potent, selective inhibitor of the noradrenalin transporter (NET) (IC 50 = 2.9 nM). Exhibits selectivity for NET against SERT (5-HT transporters) and DAT (dopamine transporters). Displays a similar structure but different pharmacological profile to citalopram (Cat. No. 1427).

Product References

3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition - 3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition

Bogeso KP, Christensen AV, Hyttel J, Liljefors T. J Med Chem. 1985 Dec;28(12):1817-28.

From the selective serotonin transporter inhibitor citalopram to the selective - From the selective serotonin transporter inhibitor citalopram to the selective

Eildal JN, Andersen J, Kristensen AS, Jorgensen AM, Bang-Andersen B, Jorgensen M, Stromgaard K. J Med Chem. 2008 May 22;51(10):3045-8.