| Name | Talsupram hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3145 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 25487-28-9 |
| Chemical Name | 1,3-Dihydro-N,3,3-trimethyl-1-phenylbenzo[c]thiophene-1-propanaminehydrochloride |
| Formula | C20H25NS.HCl |
| Molecular Weight | 347.95 |
| Purity | >98 % |
| Description | Selective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC 50 values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant. |
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McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Camp VM, Votaw JR, Nemeroff CB, Goodman MM. Nucl Med Biol. 2004 Aug;31(6):705-18.
Rowlett JK, Platt DM, Spealman RD. J Pharmacol Exp Ther. 2004 Jul;310(1):342-8. Epub 2004 Feb 25.