Tamoxifen citrate

• Supplier: Tocris Bioscience
• Catalog: 4506
• Prices: $69.00
• Sizes: 100 mg
• Function Type: Antagonist
• Cas Number: 54965-24-1
• Chemical Name: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanaminecitrate
• Formula: C26H29NO.C6H8O7
• Molecular Weight: 563.65
• Purity: >99 %
• Description: Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPER.

Product References

Non-steroidal antioestrogens--receptor binding and biological response in rat - Non-steroidal antioestrogens--receptor binding and biological response in rat

Wakeling AE, Valcaccia B, Newboult E, Green LR. J Steroid Biochem. 1984 Jan;20(1):111-20.

Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an - Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an

Paul R, Silve S, De Nys N, Dupuy PH, Bouteiller CL, Rosenfeld J, Ferrara P, Le Fur G, Casellas P, Loison G. J Pharmacol Exp Ther. 1998 Jun;285(3):1296-302.

Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage - Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage

Mehta SH, Dhandapani KM, De Sevilla LM, Webb RC, Mahesh VB, Brann DW. Neuroendocrinology. 2003 Jan;77(1):44-50.

Identity of an estrogen membrane receptor coupled to a G protein in human breast - Identity of an estrogen membrane receptor coupled to a G protein in human breast

Thomas P, Pang Y, Filardo EJ, Dong J. Endocrinology. 2005 Feb;146(2):624-32. Epub 2004 Nov 11.