Tanshinone IIA

• Supplier: Tocris Bioscience
• Catalog: 2854
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Cas Number: 568-72-9
• Chemical Name: 6,7,8,9-Tetrahydro-1,6,6-trimethylphenanthro[1,2-b]furan-10,11-dione
• Formula: C19H18O3
• Molecular Weight: 294.34
• Purity: >98 %
• Description: Major tanshinone isolated from Salvia miltiorrhiza . Inhibits NF- κ B and AP-1 DNA binding. Exhibits cytotoxic activity in a number of different cancer cells. Inhibits β -amyloid aggregation and protects PC12 cells from β -amyloid-induced apoptosis. Displays antioxidant and anti-inflammatory properties.

Product References

Growth inhibition and induction of apoptosis and differentiation of tanshinone - Growth inhibition and induction of apoptosis and differentiation of tanshinone

Wang J, Wang X, Jiang S, Yuan S, Lin P, Zhang J, Lu Y, Wang Q, Xiong Z, Wu Y, Ren J, Yang H. J Neurooncol. 2007 Mar;82(1):11-21. Epub 2006 Sep 6.

Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle - Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle

Jin UH, Suh SJ, Chang HW, Son JK, Lee SH, Son KH, Chang YC, Kim CH. J Cell Biochem. 2008 May 1;104(1):15-26.

Anticancer effects of tanshinone I in human non-small cell lung cancer. - Anticancer effects of tanshinone I in human non-small cell lung cancer.

Lee CY, Sher HF, Chen HW, Liu CC, Chen CH, Lin CS, Yang PC, Tsay HS, Chen JJ. Mol Cancer Ther. 2008 Nov;7(11):3527-38.

Tanshinone IIA protects PC12 cells from beta-amyloid(25-35)-induced apoptosis via - Tanshinone IIA protects PC12 cells from beta-amyloid(25-35)-induced apoptosis via

Dong H, Mao S, Wei J, Liu B, Zhang Z, Zhang Q, Yan M. Mol Biol Rep. 2012 Jun;39(6):6495-503.