Name | TBCA |
---|---|
Supplier | Tocris Bioscience |
Catalog | 2275 |
Prices | $179.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Cas Number | 934358-00-6 |
Chemical Name | (2E)-3-(2,3,4,5-Tetrabromophenyl)-2-propenoicacid |
Formula | C9H4Br4O2 |
Molecular Weight | 463.74 |
Purity | >98 % |
Description | Selective CK2 inhibitor (IC 50 = 110 nM). Exhibits selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases. Reduces viability of Jurkat cells in vitro . |
Supplier Page | Shop |
Shimamoto K, Lebrun B, Yasuda-Kamatani Y, Sakaitani M, Shigeri Y, Yumoto N, Nakajima T. Mol Pharmacol. 1998 Feb;53(2):195-201.
Jabaudon D, Shimamoto K, Yasuda-Kamatani Y, Scanziani M, Gahwiler BH, Gerber U. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8733-8.
Shimamoto K, Shigeri Y, Yasuda-Kamatani Y, Lebrun B, Yumoto N, Nakajima T. Bioorg Med Chem Lett. 2000 Nov 6;10(21):2407-10.
Shigeri Y, Shimamoto K, Yasuda-Kamatani Y, Seal RP, Yumoto N, Nakajima T, Amara SG. J Neurochem. 2001 Oct;79(2):297-302.