Name | TC 1 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 1223 |
Prices | $199.00, $825.00 |
Sizes | 10 mg, 50 mg |
Cas Number | 362512-81-0 |
Chemical Name | (N-(3'-Fluorophenyl)ethyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol |
Formula | C19H20FNO |
Molecular Weight | 297.37 |
Purity | >99 % |
Description | High affinity σ 1 receptor ligand that displays selectivity over σ 2 receptors (K i values are 10 and 370 nM respectively). Exhibits low affinity for dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters (K i > 10 μ M) and low affinity for dopamine D 2 receptors (K i = 1226 nM). Attenuates cocaine-induced locomotor activity in mice. |
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