TC 1698 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4300
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 787587-06-8
• Chemical Name: 2-(3-Pyridinyl)-1-azabicyclo[3.2.2]nonanedihydrochloride
• Formula: C13H18N2.2HCl
• Molecular Weight: 275.22
• Purity: >98 %
• Description: Selective nicotinic α 7 receptor agonist (EC 50 = 440 nM). Also displays weak partial agonist/antagonist activity at β -subunit-containing receptors. Neuroprotective.

Product References

The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), - The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698),

Marrero MB, Papke RL, Bhatti BS, Shaw S, Bencherif M. J Pharmacol Exp Ther. 2004 Apr;309(1):16-27. Epub 2004 Jan 13.

Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human - Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human

Papke RL, McCormack TJ, Jack BA, Wang D, Bugaj-Gaweda B, Schiff HC, Buhr JD, Waber AJ, Stokes C. Eur J Pharmacol. 2005 Nov 7;524(1-3):11-8. Epub 2005 Nov 2.