TC-DAPK 6

Name TC-DAPK 6
Supplier Tocris Bioscience
Catalog 4345
Prices $105.00, $445.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Chemical Name (4Z)-2-[(E)-2-Phenylethenyl)-4-(3-pyridinylmethylene)-5(4H)-oxazolone
Formula C17H12N2O2
Molecular Weight 276.29
Purity >98 %
Description Potent and selective, ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) (IC 50 values are 69 and 225 nM for DAPK1 and DAPK3 respectively, when assayed with 10 μ M ATP). Displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC 50 > 10 μ M).
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