| Name | TC-E 5001 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4301 |
| Prices | $139.00, $579.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 865565-29-3 |
| Chemical Name | 3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole |
| Formula | C20H19N5O3S |
| Molecular Weight | 409.46 |
| Purity | >98 % |
| Description | Dual tankyrase (TNKS) inhibitor (K d values are 79 and 28 nM for TNKS1 and TNKS2 respectively, IC 50 = 33 nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC 50 >19 μ M). Inhibits Wnt signaling and stabilizes Axin2 levels. |
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