TC-E 5002

• Supplier: Tocris Bioscience
• Catalog: 5049
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 1453071-47-0
• Chemical Name: N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine
• Formula: C15H27NO4
• Molecular Weight: 285.38
• Purity: >98 %
• Description: Selective histone demethylase KDM2/7 subfamily inhibitor (IC 50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μ M for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro .

Product References

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and - Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and

Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N. J Med Chem. 2013 Sep 26;56(18):7222-31.