Name | TCPOBOP |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4386 |
Prices | $99.00, $419.00 |
Sizes | 10 mg, 50 mg |
Function Type | Agonist |
Cas Number | 76150-91-9 |
Chemical Name | 1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene |
Formula | C16H8Cl4N2O2 |
Molecular Weight | 402.06 |
Purity | >98 % |
Description | Agonist of the constitutive androstane receptor (CAR) (EC 50 = 20 nM). Induces activity of ER1 cytochrome P450 isozymes, NADPH-cytochrome c reductase, microsomal epoxide hydrolase and glutathione S transferase. Potent mitogen; induces liver cell proliferation in mice. |
Supplier Page | Shop |
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Ledda-Columbano GM, Curto M, Piga R, Zedda AI, Menegazzi M, Sartori C, Shinozuka H, Bluethmann H, Poli V, Ciliberto G, Columbano A. Oncogene. 1998 Aug 27;17(8):1039-44.
Tzameli I, Pissios P, Schuetz EG, Moore DD. Mol Cell Biol. 2000 May;20(9):2951-8.