TCS 1102

Name TCS 1102
Supplier Tocris Bioscience
Catalog 1225
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 916141-36-1
Chemical Name N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl-2-pyrrolidinedicarboxamide
Formula C27H26N4O2S
Molecular Weight 470.59
Purity >98 %
Description Potent, dual orexin receptor antagonist (K i values are 0.2 and 3 nM for OX 2 and OX 1 receptors respectively). Inhibits ADL-orexin B-mediated locomotion following i.p. administration in vivo . Brain penetrant.
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