| Name | TCS 21311 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3869 |
| Prices | $235.00, $965.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1260181-14-3 |
| Chemical Name | 3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Formula | C27H25F3N4O4 |
| Molecular Weight | 526.51 |
| Purity | >98 % |
| Description | Potent JAK3 inhibitor (IC 50 = 8 nM). Selective for JAK3 over JAK1, JAK2 and TYK2 (IC 50 values are 1017, 2550 and 8055 nM respectively). Also inhibits GSK-3 β , PKC α and PKC θ (IC 50 values are 3, 13 and 68 nM respectively). |
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