Name | TCS 359 |
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Supplier | Tocris Bioscience |
Catalog | 4244 |
Prices | $149.00, $629.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 301305-73-7 |
Chemical Name | 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide |
Formula | C18H20N2O4S |
Molecular Weight | 360.43 |
Purity | >99 % |
Description | Potent inhibitor of FLT3 receptor tyrosine kinase (IC 50 = 42 nM) that displays selectivity over a range of other kinases. Exhibits antiproliferative effects on MV4-11 cells, a human acute myelogenous leukemia cell line expressing a constitutively active mutant FLT3 (IC 50 = 340 nM). |
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