TCS 359

Name TCS 359
Supplier Tocris Bioscience
Catalog 4244
Prices $149.00, $629.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 301305-73-7
Chemical Name 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide
Formula C18H20N2O4S
Molecular Weight 360.43
Purity >99 %
Description Potent inhibitor of FLT3 receptor tyrosine kinase (IC 50 = 42 nM) that displays selectivity over a range of other kinases. Exhibits antiproliferative effects on MV4-11 cells, a human acute myelogenous leukemia cell line expressing a constitutively active mutant FLT3 (IC 50 = 340 nM).
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