| Name | TC-S 7003 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4961 |
| Prices | $219.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 847950-09-8 |
| Chemical Name | 6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one |
| Formula | C31H30N8O |
| Molecular Weight | 530.62 |
| Purity | >98 % |
| Description | Potent inhibitor of lymphocyte specific kinase (Lck). IC 50 values are 0.007, 0.021, 0.042 and 0.20 μ M for Lck, Lyn, Src and Syk kinases respectively. Displays >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Inhibits T cell proliferation in vitro and inhibits arthritis in two in vivo models. Orally active. |
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