Name | TC-S 7005 |
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Supplier | Tocris Bioscience |
Catalog | 5088 |
Prices | $255.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Cas Number | 1082739-92-1 |
Chemical Name | 3-(1,3-Benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-isoxazolo[5,4-c]pyridin-5-amine |
Formula | C21H17N3O3 |
Molecular Weight | 359.38 |
Purity | >98 % |
Description | Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC 50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC 50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells. |
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