TC-S 7005

Name TC-S 7005
Supplier Tocris Bioscience
Catalog 5088
Prices $255.00
Sizes 10 mg
Function Type Inhibitor
Cas Number 1082739-92-1
Chemical Name 3-(1,3-Benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-isoxazolo[5,4-c]pyridin-5-amine
Formula C21H17N3O3
Molecular Weight 359.38
Purity >98 %
Description Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC 50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC 50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.
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