Tenofovir

• Supplier: Tocris Bioscience
• Catalog: 2580
• Prices: $155.00, $645.00
• Sizes: 10 mg, 50 mg
• Cas Number: 147127-20-6
• Chemical Name: (R)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonicacid
• Formula: C9H14N5O4P
• Molecular Weight: 287.21
• Purity: >99 %
• Description: Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC 50 = 1.5 μ M). Antiviral agent.

Product References

Prevention of SIV infection in macaques by - Prevention of SIV infection in macaques by

Tsai CC, Follis KE, Sabo A, Beck TW, Grant RF, Bischofberger N, Benveniste RE, Black R. Science. 1995 Nov 17;270(5239):1197-9.

9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian - 9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian

Van Rompay KK, Cherrington JM, Marthas ML, Berardi CJ, Mulato AS, Spinner A, Tarara RP, Canfield DR, Telm S, Bischofberger N, Pedersen NC. Antimicrob Agents Chemother. 1996 Nov;40(11):2586-91.

Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, - Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor,

Suo Z, Johnson KA. J Biol Chem. 1998 Oct 16;273(42):27250-8.