(-)-Terreic acid

• Supplier: Tocris Bioscience
• Catalog: 5069
• Prices: $175.00
• Sizes: 10 mg
• Function Type: Inhibitor
• Cas Number: 121-40-4
• Chemical Name: (1R,6S)-3-Hydroxy-4-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione
• Formula: C7H6O4
• Molecular Weight: 154.12
• Purity: >99 %
• Description: Selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits the interaction between PKCbII and BTK (IC 50 ~ 30 mM) and the catalytic activity of BTK but does not affect the activity of PKC. Has little effect on the activities of Lyn, Syk, PKA, casein kinase I, ERK1, ERK2 and p38 kinases.

Product References

Studies on terreic acid. - Studies on terreic acid.

Yamamoto H, Moriyama K, Jinnouchi H, Yagishita K. Jpn J Antibiot. 1980 Mar;33(3):320-8.

In vivo and in vitro studies on the binding nature of terreic acid with - In vivo and in vitro studies on the binding nature of terreic acid with

Subramanian T, Namasivayam KM, Shanmugasundaram ER. Toxicol Lett. 1982 Feb;10(2-3):249-53.

Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase. - Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase.

Kawakami Y, Hartman SE, Kinoshita E, Suzuki H, Kitaura J, Yao L, Inagaki N, Franco A, Hata D, Maeda-Yamamoto M, Fukamachi H, Nagai H, Kawakami T. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2227-32.