4,9-Anhydrotetrodotoxin

Name 4,9-Anhydrotetrodotoxin
Supplier Tocris Bioscience
Catalog 1078
Prices $199.00
Sizes 100 µg
Function Type Blocker
Cas Number 13072-89-4
Chemical Name (4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-2-Amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-6,10-epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol
Formula C11H15N3O7
Molecular Weight 301.25
Purity >98 %
Description Potent and selective Na v 1.6 channel blocker (IC 50 values are 7.8, 341, 988, 1260, 1270, 78500 and >30000 nM for Na v 1.6, Na v 1.3, Na v 1.4, Na v 1.2, Na v 1.7, Na v 1.5 and Na v 1.8). Derivative of tetrodotoxin (Cat. No. 1078).
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Product References

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Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. - Structure-activity relations of tetrodotoxin, saxitoxin, and analogues.

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The protective action of tetrodotoxin and (+/-)-kavain on anaerobic glycolysis, - The protective action of tetrodotoxin and (+/-)-kavain on anaerobic glycolysis,

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