| Name | TFC 007 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2532 |
| Prices | $205.00, $845.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 927878-49-7 |
| Chemical Name | N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |
| Formula | C27H29N5O4 |
| Molecular Weight | 487.55 |
| Purity | >98 % |
| Description | Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor (IC 50 = 83 nM). Inhibits PGD 2 production and late phase nasal blockage in an animal model of allergic rhinitis. Exhibits negligible effects on COX-1, COX-2, 5-LOX, LTC 4 synthase, TXA 2 synthase and microsomal prostaglandin E 2 synthase. |
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