TFLLR-NH 2

• Supplier: Tocris Bioscience
• Catalog: 5108
• Prices: $269.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 197794-83-5
• Formula: C31H53N9O6
• Molecular Weight: 647.82
• Description: Peptide derived from the protease-activated receptor-1 (PAR 1 ) that acts as a PAR 1 selective agonist (EC 50 = 1.9 μ M). Stimulates PAR 1 -mediated plasma extravasation in vivo . Control Peptide RLLFT-NH 2 (Cat. No. 3393) also available.

Product References

Proteinase-activated receptors: structural requirements for activity, receptor - Proteinase-activated receptors: structural requirements for activity, receptor

Hollenberg MD, Saifeddine M, al-Ani B, Kawabata A. Can J Physiol Pharmacol. 1997 Jul;75(7):832-41.

Characterization of the protease-activated receptor-1-mediated contraction and - Characterization of the protease-activated receptor-1-mediated contraction and

Kawabata A, Kuroda R, Kuroki N, Nishikawa H, Kawai K, Araki H. Life Sci. 2000 Oct 6;67(20):2521-30.

Agonists of proteinase-activated receptor 1 induce plasma extravasation by a - Agonists of proteinase-activated receptor 1 induce plasma extravasation by a

de Garavilla L, Vergnolle N, Young SH, Ennes H, Steinhoff M, Ossovskaya VS, D'Andrea MR, Mayer EA, Wallace JL, Hollenberg MD, Andrade-Gordon P, Bunnett NW. Br J Pharmacol. 2001 Aug;133(7):975-87.