( R , R )-THC

• Supplier: Tocris Bioscience
• Catalog: 1138
• Prices: $319.00
• Sizes: 10 mg
• Function Type: Antagonist
• Cas Number: 138090-06-9
• Chemical Name: (R,R)-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
• Formula: C22H24O2
• Molecular Weight: 320.42
• Purity: >98 %
• Description: Non-steroidal, selective estrogen receptor ligand; agonist at ER α receptor (K i = 9.0 nM) and antagonist at ER β receptor (K i = 3.6 nM).

Product References

Novel ligands that function as selective estrogens or antiestrogens for estrogen - Novel ligands that function as selective estrogens or antiestrogens for estrogen

Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS. Endocrinology. 1999 Feb;140(2):800-4.

Conformational changes and coactivator recruitment by novel ligands for estrogen - Conformational changes and coactivator recruitment by novel ligands for estrogen

Kraichely DM, Sun J, Katzenellenbogen JA, Katzenellenbogen BS. Endocrinology. 2000 Oct;141(10):3534-45.