Thymosin β4

• Supplier: Tocris Bioscience
• Catalog: 1185
• Prices: $129.00
• Sizes: 100 µg
• Cas Number: 77591-33-4
• Formula: C212H350N56O78S
• Molecular Weight: 4963.49
• Description: Naturally occuring, potent regulator of actin polymerization present in human platelets at a concentration of 200 - 500 μ M. Sequesters G-actin monomers in a 1:1 ratio (K d = 0.7 - 1.0 μ M) and allows rapid filament polymerization in the presence of profilin. Implicated in wound healing, induction of MMPs, chemotaxis, angiogenesis, inflammatory processes and tumor progression.

Product References

Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering - Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering

Yu FX, Lin SC, Morrison-Bogorad M, Atkinson MA, Yin HL. J Biol Chem. 1993 Jan 5;268(1):502-9.

beta-Thymosins, small acidic peptides with multiple functions. - beta-Thymosins, small acidic peptides with multiple functions.

Huff T, Muller CS, Otto AM, Netzker R, Hannappel E. Int J Biochem Cell Biol. 2001 Mar;33(3):205-20.

Thymosin beta4 and angiogenesis: modes of action and therapeutic potential. - Thymosin beta4 and angiogenesis: modes of action and therapeutic potential.

Smart N, Rossdeutsch A, Riley PR. Angiogenesis. 2007;10(4):229-41. Epub 2007 Jul 14.