Tianeptine sodium salt

• Supplier: Tocris Bioscience
• Catalog: 4256
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Cas Number: 30123-17-2
• Chemical Name: 7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoicacidsodiumsalt
• Formula: C21H24ClN2NaO4S
• Molecular Weight: 458.93
• Purity: >99 %
• Description: Selective facilitator of 5-HT uptake in vitro and in vivo . Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC 50 > 10 μ M) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo .

Product References

Neurochemical profile of tianeptine, a new antidepressant drug. - Neurochemical profile of tianeptine, a new antidepressant drug.

Kato G, Weitsch AF. Clin Neuropharmacol. 1988;11 Suppl 2:S43-50.

Analgesic effect of tianeptine in mice. - Analgesic effect of tianeptine in mice.

Uzbay IT, Cinar MG, Aytemir M, Tuglular I. Life Sci. 1999;64(15):1313-9.

Neuroprotective properties of tianeptine: interactions with cytokines. - Neuroprotective properties of tianeptine: interactions with cytokines.

Plaisant F, Dommergues MA, Spedding M, Cecchelli R, Brillault J, Kato G, Munoz C, Gressens P. Neuropharmacology. 2003 May;44(6):801-9.