Name | Tiotropium bromide |
---|---|
Supplier | Tocris Bioscience |
Catalog | 0826 |
Prices | $179.00, $745.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 136310-93-5 |
Chemical Name | (1α,2β,4β,5α,7β)-7-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonanebromide |
Formula | C19H22BrNO4S2 |
Molecular Weight | 472.42 |
Purity | >98 % |
Description | Potent muscarinic receptor antagonist. Inhibits electrical field stimulation-induced contraction of guinea pig trachea in vitro (IC 50 = 0.17 nM). Induces smooth muscle relaxation and bronchodilation. |
Supplier Page | Shop |
Elokdah H, Abou-Gharbia M, Hennan JK, McFarlane G, Mugford CP, Krishnamurthy G, Crandall DL. J Med Chem. 2004 Jul 1;47(14):3491-4.
Simone TM, Higgins SP, Archambeault J, Higgins CE, Ginnan RG, Singer H, Higgins PJ. Cell Signal. 2015 May;27(5):923-33.