TMS

• Supplier: Tocris Bioscience
• Catalog: 4253
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 24144-92-1
• Chemical Name: 1-[2,(3,5-Dimethoxyphenyl)ethenyl]-2,4-dimethoxybenzene
• Formula: C18H20O4
• Molecular Weight: 300.35
• Purity: >98 %
• Description: Potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC 50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. Inhibits cancer cell growth in vitro .

Product References

A new selective and potent inhibitor of human cytochrome P450 1B1 and its - A new selective and potent inhibitor of human cytochrome P450 1B1 and its

Chun YJ, Kim S, Kim D, Lee SK, Guengerich FP. Cancer Res. 2001 Nov 15;61(22):8164-70.

Resveratrol analog, 3,5,2',4'-tetramethoxy-trans-stilbene, potentiates the - Resveratrol analog, 3,5,2',4'-tetramethoxy-trans-stilbene, potentiates the

Nam KA, Kim S, Heo YH, Lee SK. Arch Pharm Res. 2001 Oct;24(5):441-5.

Design, synthesis, and discovery of novel trans-stilbene analogues as potent and - Design, synthesis, and discovery of novel trans-stilbene analogues as potent and

Kim S, Ko H, Park JE, Jung S, Lee SK, Chun YJ. J Med Chem. 2002 Jan 3;45(1):160-4.