Tocrifluor T1117

• Supplier: Tocris Bioscience
• Catalog: 3909
• Prices: $269.00
• Sizes: 100 µg
• Cas Number: 1186195-59-4
• Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
• Formula: C56H53Cl2N7O5
• Molecular Weight: 974.97
• Purity: >95 %
• Description: Fluorescent form of AM 251 (Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity.

Product References

Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors - Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors

Daly CJ, Ross RA, Whyte J, Henstridge CM, Irving AJ, McGrath JC. Br J Pharmacol. 2010 Feb;159(4):787-96.

Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts - Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts

Sylantyev S, Jensen TP, Ross RA, Rusakov DA. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5193-8. doi:

Beyond radio-displacement techniques for identification of CB1 ligands: the first - Beyond radio-displacement techniques for identification of CB1 ligands: the first

Bruno A, Lembo F, Novellino E, Stornaiuolo M, Marinelli L. Sci Rep. 2014 Jan 20;4:3757.