Tomoxetine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 5527
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 82248-59-7
• Chemical Name: (R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanaminehydrochloride
• Formula: C17H21NO.HCl
• Molecular Weight: 291.82
• Purity: >99 %
• Description: Potent and selective noradrenalin re-uptake inhibitor (K i values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (K i > 1 μ M). Antidepressant.

Product References

A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat - A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat

Wong DT, Threlkeld PG, Best KL, Bymaster FP. J Pharmacol Exp Ther. 1982 Jul;222(1):61-5.

Atomoxetine increases extracellular levels of norepinephrine and dopamine in - Atomoxetine increases extracellular levels of norepinephrine and dopamine in

Bymaster FP, Katner JS, Nelson DL, Hemrick-Luecke SK, Threlkeld PG, Heiligenstein JH, Morin SM, Gehlert DR, Perry KW. Neuropsychopharmacology. 2002 Nov;27(5):699-711.