| Name | TRAM 34 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1558 |
| Prices | $129.00, $535.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Blocker |
| Cas Number | 289905-88-0 |
| Chemical Name | 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole |
| Formula | C22H17ClN2 |
| Molecular Weight | 344.84 |
| Purity | >99 % |
| Description | Potent and highly selective blocker of intermediate conductance Ca 2+ -activated K + channels (K Ca 3.1) (K d = 20 nM). Exhibits 200-1500-fold selectivity over K V , BK Ca , K Ca 2, Na + , CRAC and Cl - channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli. |
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Schilling T, Eder C. Pflugers Arch. 2007 Jul;454(4):559-63. Epub 2007 Feb 23.
Wang J, Xu YQ, Liang YY, Gongora R, Warnock DG, Ma HP. Pflugers Arch. 2007 Sep;454(6):945-56. Epub 2007 Apr 12.