Trifluorothymidine

• Supplier: Tocris Bioscience
• Catalog: 5227
• Prices: $105.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 70-00-8
• Chemical Name: α,α,α-Trifluorothymidine
• Formula: C10H11F3N2O5
• Molecular Weight: 296.2
• Purity: >98 %
• Description: Nucleoside analog; inhibitor of thymidylate synthase. Incorporation of the triphosphate form into DNA induces DNA fragmentation. Exhibits antitumor activity.

Product References

Potentiation of the antitumor activity of alpha, alpha, alpha-trifluorothymidine - Potentiation of the antitumor activity of alpha, alpha, alpha-trifluorothymidine

Emura T, Suzuki N, Fujioka A, Ohshimo H, Fukushima M. Int J Oncol. 2005 Aug;27(2):449-55.

Involvement of concentrative nucleoside transporter 1 in intestinal absorption of - Involvement of concentrative nucleoside transporter 1 in intestinal absorption of

Okayama T, Yoshisue K, Kuwata K, Komuro M, Ohta S, Nagayama S. J Pharmacol Exp Ther. 2012 Feb;340(2):457-62.