Tunicamycin

Name Tunicamycin
Supplier Tocris Bioscience
Catalog 4601
Prices $159.00
Sizes 10 mg
Cas Number 11089-65-9
Chemical Name TunicamycinfromStreptomycessp.
Formula C39H64N4O16(tunicamycinC,n=10)
Molecular Weight 844.95
Description Antibiotic; inhibits GlcNAc phosphotransferase (GPT). Blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. Activity induces ER stress and causes G 1 arrest; can be used to induce autophagy. Tunicamycin contains four main components as follows: Homolog A, n=8, C 37 H 60 N 4 O 16 , molecular weight = 816.90 Homolog B, n=9, C 38 H 62 N 4 O 16 , molecular weight = 830.93 Homolog C, n=10, C 39 H 64 N 4 O 16 , molecular weight = 844.95 Homolog D, n=11, C 40 H 66 N 4 O 16 , molecular weight = 858.99 The composition of this product will vary from batch to batch and can be found on the relevant certificate of analysis.
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Product References

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The hepatitis B virus precore protein is retrotransported from endoplasmic - The hepatitis B virus precore protein is retrotransported from endoplasmic

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Primary murine airway smooth muscle cells exposed to poly(I,C) or tunicamycin - Primary murine airway smooth muscle cells exposed to poly(I,C) or tunicamycin

Lauer ME, Mukhopadhyay D, Fulop C, de la Motte CA, Majors AK, Hascall VC. J Biol Chem. 2009 Feb 20;284(8):5299-312.