UK 14,304

• Supplier: Tocris Bioscience
• Catalog: 0775
• Prices: $115.00, $485.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 59803-98-4
• Chemical Name: 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
• Formula: C11H10BrN5
• Molecular Weight: 292.14
• Description: Full α 2 adrenergic agonist. Centrally active following systemic administration in vivo . Also available as part of the α 2 -Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™ . Water soluble salt version UK 14,304 tartrate (Cat. No. 2466) also available.

Product References

Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity - Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity

Andorn AC, Carlson MA, Gilkeson RC. Life Sci. 1988;43(22):1805-12.

Gene targeting--homing in on alpha 2-adrenoceptor-subtype function. - Gene targeting--homing in on alpha 2-adrenoceptor-subtype function.

MacDonald E, Kobilka BK, Scheinin M. Trends Pharmacol Sci. 1997 Jun;18(6):211-9.

Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in - Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in

Chopin P, Colpaert FC, Marien M. J Pharmacol Exp Ther. 1999 Feb;288(2):798-804.