UNC 3230

Name UNC 3230
Supplier Tocris Bioscience
Catalog 4905
Prices $185.00, $755.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1031602-63-7
Chemical Name 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide
Formula C17H20N4O2S
Molecular Weight 344.43
Purity >99 %
Description Potent and selective PIP5K1C inhibitor (IC 50 = 41 nM). Exhibits selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. Reduces PIP 2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro . Reduces nociception in mouse models of chronic pain.
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