Urotensin II (human)

• Supplier: Tocris Bioscience
• Catalog: 1605
• Prices: $265.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 251293-28-4
• Formula: C64H85N13O18S2
• Molecular Weight: 1388.57
• Description: Potent endogenous peptide agonist for the urotensin-II receptor (EC 50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo , effects which vary between species. Also has been shown to mediate bronchoconstriction.

Product References

Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals - Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals

Coulouarn Y, Lihrmann I, Jegou S, Anouar Y, Tostivint H, Beauvillain JC, Conlon JM, Bern HA, Vaudry H. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15803-8.

Identification of the natural ligand of an orphan G-protein-coupled receptor - Identification of the natural ligand of an orphan G-protein-coupled receptor

Nothacker HP, Wang Z, McNeill AM, Saito Y, Merten S, O'Dowd B, Duckles SP, Civelli O. Nat Cell Biol. 1999 Oct;1(6):383-5.

Is urotensin-II the new endothelin? - Is urotensin-II the new endothelin?

Maguire JJ, Davenport AP. Br J Pharmacol. 2002 Nov;137(5):579-88.