UVI 3003

• Supplier: Tocris Bioscience
• Catalog: 3279
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 847239-17-2
• Chemical Name: 3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoicacid
• Formula: C28H36O4
• Molecular Weight: 436.58
• Purity: >98 %
• Description: RXR antagonist; displays high RXR binding affinity. Does not affect the corepressor interaction capacity of the RAR α subunit within the context of the RAR-RXR heterodimer.

Product References

Activation of RXR-PPAR heterodimers by organotin environmental endocrine - Activation of RXR-PPAR heterodimers by organotin environmental endocrine

le Maire A, Grimaldi M, Roecklin D, Dagnino S, Vivat-Hannah V, Balaguer P, Bourguet W. EMBO Rep. 2009 Apr;10(4):367-73.

Modulating retinoid X receptor with a series of - Modulating retinoid X receptor with a series of

Perez Santin E, Germain P, Quillard F, Khanwalkar H, Rodriguez-Barrios F, Gronemeyer H, de Lera AR, Bourguet W. J Med Chem. 2009 May 28;52(10):3150-8.