Valinomycin

Name Valinomycin
Supplier Tocris Bioscience
Catalog 3048
Prices $59.00, $225.00
Sizes 10 mg, 50 mg
Cas Number 2001-95-8
Chemical Name Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
Formula C54H90N6O18
Molecular Weight 1111.32
Description Selective K + ionophore (K 0.5 values are 48, 73, 75, 93 and 246 mM for K + , Rb + , Cs + , Na + and Li + respectively) that transports K + across biological and artificial lipid membranes. Inhibits Ca 2+ -ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro .
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