Name | Valinomycin |
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Supplier | Tocris Bioscience |
Catalog | 3048 |
Prices | $59.00, $225.00 |
Sizes | 10 mg, 50 mg |
Cas Number | 2001-95-8 |
Chemical Name | Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl) |
Formula | C54H90N6O18 |
Molecular Weight | 1111.32 |
Description | Selective K + ionophore (K 0.5 values are 48, 73, 75, 93 and 246 mM for K + , Rb + , Cs + , Na + and Li + respectively) that transports K + across biological and artificial lipid membranes. Inhibits Ca 2+ -ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro . |
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