Veratridine

• Supplier: Tocris Bioscience
• Catalog: 0654
• Prices: $95.00, $399.00
• Sizes: 10 mg, 50 mg
• Cas Number: 71-62-5
• Chemical Name: 4α,9-Epoxy-3β-veratroyloxy-5β-cevan-4β,12,14,16β,17,20-hexaol
• Formula: C36H51NO11
• Molecular Weight: 673.79
• Purity: >98 %
• Description: Voltage-gated Na + channel opener; increases intracellular Ca 2+ with no effect on the Na + /Ca 2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na + permeability and depolarizes excitable tissues.

Product References

Purification, solubility, and pKa of veratridine. - Purification, solubility, and pKa of veratridine.

McKinney LC, Chakraverty S, De Weer P. Anal Biochem. 1986 Feb 15;153(1):33-8.

Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ - Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+

Maroto R, De la Fuente MT, Artalejo AR, Abad F, Lopez MG, Garcia-Sancho J, Garcia AG. Eur J Pharmacol. 1994 Aug 3;270(4):331-9.

Mechanism of the persistent sodium current activator veratridine-evoked Ca - Mechanism of the persistent sodium current activator veratridine-evoked Ca

Fekete A, Franklin L, Ikemoto T, Rozsa B, Lendvai B, Sylvester Vizi E, Zelles T. J Neurochem. 2009 Nov;111(3):745-56.