Viomycin

Name Viomycin
Supplier Tocris Bioscience
Catalog 0757
Prices $159.00
Sizes 10 mg
Cas Number 32988-50-4
Chemical Name (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamidedisulfate
Formula C25H43N13O10.2H2SO4
Molecular Weight 881.85
Description Member of the tuberactinomycin family of antibiotics. Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates trans -cleavage of the Neurospora VS ribozyme.
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Product References

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The antibiotic viomycin traps the ribosome in an intermediate state of - The antibiotic viomycin traps the ribosome in an intermediate state of

Ermolenko DN, Spiegel PC, Majumdar ZK, Hickerson RP, Clegg RM, Noller HF. Nat Struct Mol Biol. 2007 Jun;14(6):493-7. Epub 2007 May 21.