Voglibose

Name Voglibose
Supplier Tocris Bioscience
Catalog 3392
Prices $169.00, $705.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 83480-29-9
Chemical Name 3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol
Formula C10H21NO7
Molecular Weight 267.28
Description Orally active α -glucosidase inhibitor (IC 50 values are 3.9 and 6.4 nM at sucrase and maltase respectively). Increases glucagon-like peptide 1 (GLP-1) secretion and decreases food consumption in ob/ob mice, and reduces plasma concentrations of glucose, triglycerides and insulin in Wistar fatty rats. Exhibits antidiabetic and antiobesity activity in vivo .
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Product References

Effect of an intestinal disaccharidase inhibitor (AO-128) on obesity and - Effect of an intestinal disaccharidase inhibitor (AO-128) on obesity and

Matsuo T, Odaka H, Ikeda H. Am J Clin Nutr. 1992 Jan;55(1 Suppl):314S-317S.

Alpha-glucosidase inhibition assay in an enzyme-immobilized amino-microplate. - Alpha-glucosidase inhibition assay in an enzyme-immobilized amino-microplate.

Matsui T, Shimada M, Saito N, Matsumoto K. Anal Sci. 2009 Apr;25(4):559-62.

Chronic administration of voglibose, an alpha-glucosidase inhibitor, increases - Chronic administration of voglibose, an alpha-glucosidase inhibitor, increases

Moritoh Y, Takeuchi K, Hazama M. J Pharmacol Exp Ther. 2009 May;329(2):669-76.