d[Leu 4 ,Lys 8 ]-VP

• Supplier: Tocris Bioscience
• Catalog: 3760
• Prices: $289.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 42061-33-6
• Formula: C47H67N11O11S2
• Molecular Weight: 1026.2
• Description: Selective vasopressin V 1B receptor agonist (K i values are 0.16, 64, 100 and 3800 nM for V 1B , oxytocin, V 2 and V 1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities.

Product References

Design and synthesis of the first selective agonists for the rat vasopressin - Design and synthesis of the first selective agonists for the rat vasopressin

Pena A, Murat B, Trueba M, Ventura MA, Wo NC, Szeto HH, Cheng LL, Stoev S, Guillon G, Manning M. J Med Chem. 2007 Feb 22;50(4):835-47.

Pharmacological and physiological characterization of d[Leu4, Lys8]vasopressin, - Pharmacological and physiological characterization of d[Leu4, Lys8]vasopressin,

Pena A, Murat B, Trueba M, Ventura MA, Bertrand G, Cheng LL, Stoev S, Szeto HH, Wo N, Brossard G, Serradeil-Le Gal C, Manning M, Guillon G. Endocrinology. 2007 Sep;148(9):4136-46. Epub 2007 May 10.