VPC 23019

• Supplier: Tocris Bioscience
• Catalog: 3127
• Prices: $299.00
• Sizes: 10 mg
• Function Type: Antagonist
• Cas Number: 449173-19-7
• Chemical Name: 2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
• Formula: C17H29N2O5P
• Molecular Weight: 372.4
• Purity: >95 %
• Description: Sphingosine-1-phosphate receptor antagonist; inhibits S1P 1 and S1P 3 receptors (pK i values are 7.86 and 5.93 respectively).

Product References

Sphingosine 1-phosphate analogs as receptor antagonists. - Sphingosine 1-phosphate analogs as receptor antagonists.

Davis MD, Clemens JJ, Macdonald TL, Lynch KR. J Biol Chem. 2005 Mar 18;280(11):9833-41. Epub 2004 Dec 8.

The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium - The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium

Aoki S, Yatomi Y, Shimosawa T, Yamashita H, Kitayama J, Tsuno NH, Takahashi K, Ozaki Y. J Thromb Haemost. 2007 Jun;5(6):1292-301.

High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic - High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic

Mihovilovic M, Robinette JB, DeKroon RM, Sullivan PM, Strittmatter WJ. J Lipid Res. 2007 Apr;48(4):806-15. Epub 2007 Jan 30.