| Name | VTP 27999 trifluoroacetate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4195 |
| Prices | $239.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 1013937-63-7 |
| Chemical Name | MethylN-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamatetrifluoroacetate |
| Formula | C26H41ClN4O5.CF3CO2H |
| Molecular Weight | 639.1 |
| Purity | >97 % |
| Description | Highly potent and selective renin inhibitor (IC 50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491). |
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