| Name | VU 0364770 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4171 |
| Prices | $159.00, $665.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Modulator |
| Cas Number | 61350-00-3 |
| Chemical Name | N-(3-Chlorophenyl)-2-pyridinecarboxamide |
| Formula | C12H9ClN2O |
| Molecular Weight | 232.67 |
| Purity | >99 % |
| Description | Positive allosteric modulator at mGlu 4 receptors (EC 50 = 290 nM in mGlu 4 -expressing HEK 293 cells). Reverses haloperidol-induced catalepsy in rats; prevents attentional deficit and forelimb asymmetry in a rodent model of Parkinson's disease. Exhibits affinity for MAO-B and MAO-A (K i values are 0.72 μ M and 8.5 μ M respectively). Brain penetrant. |
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